Complete nucleotide sequence of an Escherichia coli sequence type 410 strain carrying blaNDM-5 on an IncF multidrug resistance plasmid and blaOXA-181 on an IncX3 plasmid

Abstract

Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored blaNDM-5 and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and blaOXA-181. E. coli isolates with both blaNDM-5 and blaOXA-181 carbapenemases are rare.