5'-(CGA)n sequence-assisted pH-controlled assembly of supramolecular DNA nanostructure

Abstract

Herein, the DNA strands containing 5-(CGA)n and consecutive guanines are used to construct supramolecular DNA nanostructures that are size-controlled by pH values. Additionally, the introduction of thymine linkers within DNA nanostructures is necessary to maintain the stability of long-sized nanostructures. This work also demonstrates a method for accurately building DNA nanostructures.