Chemical constituents and antimicrobial activity of soil fungus aspergillus sp. FRIZ12

Abstract

The present work reports the isolation of nine biomass compounds of soil fungus Aspergillus sp. FRIZ12. The compounds 2-benzyl-4H-pyran-4-one (1), flavasperone (2), 5-(hydroxymethyl) furfural (3), uridin (4), ergosterol (5), ergosterol peroxide (6), cerivisterol (7), stigmasterol (8) and sitosterol (9) were isolated by chromatographic methods, and the structures were identified by NMR, MS, and comparison with literature data. Compound 1 is being reported for the first time in the genus Aspergillus and for the second time as a natural product. Compounds 1 and 2 showed moderate antimicrobial activity.