P685 Patient’s performance and feedback by using home test faecal calprotectin as an objective reported outcome

Abstract

Background: Inflammatory bowel disease (IBD) causes ulcerations, stricture, and perforation and also carries the risk of colorectal cancer. To reduce long-standing IBD complications, the treatment goal in IBD patients is mucosal healing. Faecal calprotectin (fC) level is a predictive marker of mucosal healing in IBD patients. We aimed to compare the correlation between the smartphone-based IBDocR home testing system and the traditional professional, laboratorybased methods. Also, would like to explore the patients' performance as well as feedback by using this home test system as an objective patient-reported outcome. Method(s): This was a prospective study. IBD patients were enrolled consecutively at the Out Patient Clinic whenever they have the smartphone that could download the home test software. Faecal calprotectin was assessed by using both the laboratory test (Quantum Blue Calprotectin High Range Rapid Test) and home test (IBDoc) with the same stool sample. The correlation between Quantum Blue test and IBDoc was analysed by the Pearson method. Meanwhile, a questionnaire was evaluated for patients' preference after they performing the test. Patients were asked about their age, sex, the highest level of education they had completed. Their disease status, drug compliance, their experience and expectation, preference of using IBDoc were evaluated. Result(s): A total of 51 patients (23 Crohn's disease/27 ulcerative colitis and one indeterminate IBD) with 68 tests, and 49 questionnaires were included. The correlation between Quantum Blue test and IBDoc is r = 0.776 (p < 0.0001). More than 80% patients were high educated. 96% patients used smartphone for more than 3 years. After the test, 56% patients felt easy to perform the IBDoc. 96 % patients felt satisfied to using the IBDoc, and 70% of them preferred to use the home test system for future monitoring if the price is acceptable. (Figure presented) Conclusion(s): The correlation between Quantum blue test and IBDoc results was good. The use of IBDoc to detect faecal calprotectin is feasible and can be managed by the patients at home. Patients preferred to use the home test system for their disease monitoring and as an objective patient reported outcome.