Journal ArticleOPEN ACCESS

PSPC1 potentiates TGF-β-dependent metastatic dissemination

Molecular and Cellular Oncology (2018) 5(4)
DOI: 10.1080/23723556.2018.1472058
7Citations
Citations of this article
8Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Metastatic reprogramming toward malignant tumor progression relies on the activation of oncogenic regulators, yet the cellular determinants remain elucidated. Through identification of aberrant prognostic cancer genes, we identified paraspeckle component 1 (PSPC1) functions as a master activator of metastatic reprogramming by activating epithelial-to-mesenchymal transition (EMT), stemness and TGF-β1 pro-metastatic switch.

Author supplied keywords

Cite

CITATION STYLE

APA

Yeh, H. W., & Jou, Y. S. (2018). PSPC1 potentiates TGF-β-dependent metastatic dissemination. Molecular and Cellular Oncology, 5(4). https://doi.org/10.1080/23723556.2018.1472058

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free