Mononuclear phagocyte antimicrobial and antitumor activity: The role of oxygen intermediates

Abstract

Recent work in this laboratory has been directed at examining mononuclear phagocyte generation of reactive oxygen intermediates and the role of these products in macrophage antimicrobial and antitumor activity. Although our observations are derived primarily from the mouse peritoneal macrophage model, similar findings are currently being made with human monocytes as well.