How should we bootstrap allozyme data?

Abstract

The use of the bootstrap to estimate the distribution of statistics from allozyme data is examined. The different loci are often used as the unit of resampling. Since the interpretation and validity of the bootstrap is affected by the unit of resampling, and since resampling over loci, in most practical cases, does not conform to the three basic assumptions of the bootstrap, this method should be avoided. Resampling over individual genotypes may provide a valid alternative approach. © 1995 The Genetical Society of Great Britain.