Overview: Global burden of liver disease

Abstract

About 2 million deaths occur annually, and 4% of all deaths are caused by liver disease, which ranks as the 11 leading cause of death worldwide. This review includes the different kinds of liver disorders and their global prevalence. It focuses primarily on areas where significant new data is available, such as drug-induced liver injury, acute chronic liver disease, hepatocellular carcinoma, non-alcoholic fatty liver disease, alcoholic liver disease, and viral hepatitis. Most deaths are attributed to complications arising from hepatocellular carcinoma and cirrhosis. Obesity in Early life is an independent risk factor for cancer and cirrhosis. In the western world, alcohol is the primary cause of liver cirrhosis. It also covers some special considerations, such as hepatic conditions during COVID-19 and pregnancy, with a retrospective study. Additionally, we cover important data on sign symptoms, prevention, diagnosis with specialized techniques, and treatment with various drugs.