Strong epidemiologic evidence correlates tobacco use with a variety of serious adverse health effects, but the biological mechanisms that produce these effects remain elusive.
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Charles, P. C., Alder, B. D., Hilliard, E. G., Schisler, J. C., Lineberger, R. E., Parker, J. S., … Stouffer, G. A. (2008). Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males. BMC Medical Genomics, 1(1). https://doi.org/10.1186/1755-8794-1-38
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