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Interactome analysis brings splicing into focus

Genome Biology (2015) 16(1)
DOI: 10.1186/s13059-015-0707-0
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Abstract

The spliceosome is a huge molecular machine that assembles dynamically onto its pre-mRNA substrates. A new study based on interactome analysis provides clues about how splicing-regulatory proteins modulate assembly of the spliceosome to either activate or repress splicing.

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Dominguez, D., & Burge, C. B. (2015). Interactome analysis brings splicing into focus. Genome Biology, 16(1). https://doi.org/10.1186/s13059-015-0707-0

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