Cadherin

Abstract

Cadherins are transmembrane proteins involved in the formation of adhesive bonds between cells. Protein plays a key role in several important processes during embryogenesis, such as the formation of gastrula, neurula, and organogenesis. Adhesion based on this protein is necessary to maintain the proper architecture of tissues in organisms. Despite the fact that cadherins have been discovered for over 40 years, their development is still slow and requires significant financial outlays. However, their incorrect expression leads to oncogenesis and metastasis. Therefore, a better understanding of cadherins is critical to cancer clinical applications, especially as therapeutic targets. Understanding how Ncadherin influences cell behavior will enable the development of therapies to combat its activity and prevent cancer cell growth, invasion and metastasis. Adhesion molecules are promising new targets in the treatment of cancer but could also be useful in predicting patient prognosis in human and veterinary medicine.