Hereditary spastic paraplegia presenting as limb dystonia with a rare spg7 mutation

Abstract

Hereditary spastic paraplegias (HSPs) are rare neurologic disorders that are genetically and clinically heterogeneous. They may be categorized as pure (pyramidal) or complex (including other neurologic signs and symptoms). Spastic paraplegia type 7 (SPG7) is an autosomal recessive type of HSP that clinically encompasses pure and complex forms.1.