Occupational Stress and Work-Life Balance: A Study of Female Faculties of Central Universities in Delhi, India

Abstract

Objectives: The aim of this study was to examine the relationship between serum levels of uric acid (UA) and 1,5-anhydroglucitol (1,5-AG) in elderly subjects (60. years or older; mean age, 73.0. ±. 7.2. years) with and without type 2 diabetes mellitus (DM). Methods: Subjects with DM (n=97) and without DM (n=360) were recruited from among our outpatients (estimated glomerular filtration rate≥45mL min-1 1.73m-2, and urine protein equivalent to <1.0g/L), and a cross-sectional study was performed with simple linear regression and stepwise multiple linear regression analyses. Results: The mean serum UA levels of men were significantly higher than those of women in both groups. The mean serum 1,5-AG levels of men were significantly higher than those of women in the non-DM group. There were positive correlations (indicated by Pearson's correlation coefficients) between serum UA levels and 1,5-anhydroglucitol levels in all patients and in both men and women. Simple linear regression and multiple linear regression analyses showed that the serum 1,5-AG levels were significantly and positively correlated with the serum UA level in both the non-DM group and the DM group. In the non-DM group, HbA1c levels, as well as 1,5-AG levels, were positively correlated with serum UA levels. Furthermore, the correlation between 1,5-AG and UA levels was stronger in subjects with DM than in subjects without DM. Conclusions: These results suggest that the serum 1,5-AG level is an independent factor associated with serum UA levels in the nondiabetic state, as in DM. © 2013 The Canadian Society of Clinical Chemists.