Demonstration of treatment response to Trans-arterial Radio-embolization (TARE) on 68Ga-DOTANOC PET/CT in a patient with metastatic neuroendocrine tumor

Abstract

Here we report a 31-year-old man with a peri-ampullary neuroendocrine tumor (NET), who underwent 68Ga DOTANOC-PET/CT for recurrence evaluation, which revealed isolated metastatic lesion in liver segment V. He underwent trans-arterial radio-embolization (TARE) of the isolated hepatic metastasis with 188Rhenium-microspheres in a lipiodol matrix. The second 68Ga DOTANOC-PET/CT was performed one month after the TARE therapy revealed resolution of the tracer uptake with good retention of the lipiodol complex replacing the metastasis suggesting a complete response.