Anti-bacterial Activity of Methanolic Fruits Extract of Acacia nilotica (L.)

Abstract

Acacia nilotica (L.) is used to treat different ailments for instance cold, congestion, fever, gallbladder, hemorrhage, hemorrhoids, leucorrhoea, ophthalmic, sclerosis, small pox, intestinal pains and acute diarrhea. Other preparations are used for gargle, toothache, ophthalmic and syphilitic ulcers. The fruits of A. nilotica were tested against eight standard bacterial species: two Gram-positive bacteria viz, Enterococcus feacalis and Staphylococcus aureus, six Gram-negative bacterial strains Escherichia coli, Pseudomonas aeruginosa, Shigella Sonnei, Salmonella Para A, Klebsiella pneumoniae and Proteus mirabilis using the disc diffusion method. Antibacterial activity of fixed oil of A. nilotica dissolved in methanol (1:10), showed high activity against the Gram-negative bacteria (P. aeruginosa & E. coli) (18 & 14 mm). It also showed against Gram positive bacteria (S. aureus & B. subtilis) (14 & 13 mm) and against (C. albicans) (14 mm). This study conducted of A. nilotica fruits proved to have potent activities against antibacterial activity in vitro.