Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes

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Abstract

Combining the numerous advantages of using light as a stimulus, simple free radical random copolymerization, and the easy, all-aqueous preparation of polyelectrolyte complexes (PECs), we prepared photolabile PEC nanoparticles and demonstrated their rapid degradation under UV light. As a proof of concept demonstration, the dye Nile Red was encapsulated in the PECs and successfully released into the surrounding solution as the polyelectrolyte nanocomplex carriers dissolved upon light irradiation.

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Hu, X., Feeney, M. J., McIntosh, E., Mullahoo, J., Jia, F., Xu, Q., & Thomas, S. W. (2016). Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes. ACS Applied Materials and Interfaces, 8(36), 23517–23522. https://doi.org/10.1021/acsami.6b07366

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