1254 The Role of Psidii Guava Leaf Extract to Increase Platelet Level in Dengue Virus Infection

Abstract

Posters 621 4.0±3.8 years, 57,4% were male and a past history of allergy or immunodeficiency was reported in 26.7%. The most frequent clinical manifestations were mucocutaneous (51.6%), followed by cardiovascular (14.4%) and gastrointestinal (12.2%). The drugs most often implicated were antibiotics (40.3%), especially vancomycin (19.7%) and amoxicillin-clavulanate (18.4%), followed by chemotherapeutic agents (8.0%), vaccines (6.9%) and steroids (5.9%). Intravenous administration was associated with 54,3% of ADR and the time from first drug administration to ADR was > 48 hours in 51.6%. The reactions were mild in 83.5%, but 3 cases required admission to ICU, with one fatality. Only 14 children (7.4%) were referred to a consultation for follow-up. Background: The pathogenesis of DHF is still unknown; ADE & virulency of dengue virus caused plasma leakage thrombocytopenia and haemorrhagic clinical manifestation of DHF cases; resuscitation fluid and increasing thrombocyte to prevent severity of Dengue Haemorrhagic cases.