Effects of Hypothyroidism on Total Cholesterol, Triglycerides and LDL

Abstract

Abstract: Hypothyroidism is an important metabolic disorder and is associated with many biochemical abnormalities.Thyroid hormones are involved in regulation of lipids and lipoprotein metabolism, therefore hypothyroidism inducesignificant change in lipid levels. A cross sectional study was done in our population to evaluate lipid profile status ofhypothyroid patients compared to healthy euthyroid persons. The objective of our study was to see the effect ofHypothyroidism on Total Cholesterol, Triglycerides and LDL. Our study was conducted at Sree Balaji Medical Collegeand Hospital Chromepet, Chennai from November 2015 to April 2016. Blood samples and data were collected frompatients attending the hospital. A total of 100 cases were included in this study. 100 cases with normal thyroid profilewere taken as control. Serum FT3, FT4, TSH, Total cholesterol, LDL-C, HDL-C, and Triglycerides were estimated inthese patients. Total cholesterol and LDL-C was significantly raised in Hypothyroidism there by, indicating the need formonitoring of lipid levels in patients with Hypothyroidism. However, there was no significant association of lipid levelsin control group. Keywords: Hypothyroidism, Total Cholesterol, Triglycerides, LDL Cholesterol