Theprotoberberine→spirobenzylisoquinoline→ dibenzocyclopentbazepine rearrangement

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Abstract

Base-catalysed rearrangement of the monophenolic dihydroprotoberberine salts (5) and (7) leads to the spirobenzylisoquinolines (6) and (8) respectively, while rearrangement of the salt (9) furnishes the dibenzocyclopentbazepine (14).

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Shamma, M., & Nugent, J. F. (1971). Theprotoberberine→spirobenzylisoquinoline→ dibenzocyclopentbazepine rearrangement. Journal of the Chemical Society D: Chemical Communications, (24). https://doi.org/10.1039/C2971001642b

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