cophesim: A comprehensive phenotype simulator for testing novel association methods

Abstract

Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present cophesim, a software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of cophesim can be used as a direct input for different genome wide association study tools. cophesim is available from https://bitbucket.org/izhbannikov/cophesim.