Impulse control disorders in Parkinson's disease: A systematic review on risk factors and pathophysiology

Abstract

Aim: Purpose of this review is to evaluate the potential risk factors that may predispose to the development of Impulse control disorders (ICDs) in Parkinson's Disease (PD) patients, including the effects of dopaminergic therapy. Methods: This descriptive review was conducted to identificate risk factors that could cause impulsive control disorders in PD. Studies were found on PubMed (2010–2018), Web Of Science (January 2010–July 2018) and Cochrane (2010–2018) databases. Results: The data suggest that intrinsic and extrinsic factors may be involved in the development of behavioral complications. To date, the link between PD and the development of ICDs is not very clear, but studies highlight the existence of a predisposition to ICDs in the presence of risk factors. Conclusions: A better assessment of the behavioral disorders of PD may be useful in the rehabilitative intervention for increasing the quality of life.