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A poly(amidoamine) dendrimer-based drug carrier for delivering DOX to gliomas cells

RSC Advances (2017) 7(25) 15475-15481
DOI: 10.1039/C7RA00713B
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Abstract

A drug delivery carrier G4-FA-PEG with PEG and FA modified on the periphery of G4.0 poly(amidoamine) (PAMAM) dendrimer was synthesized, and doxorubicin (DOX) was encapsulated in the interior. The in vitro cytotoxicity and cellular uptake in gliomas cells were both enhanced via a FR-mediated endocytosis pathway.

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Li, Y., He, H., Lu, W., & Jia, X. (2017). A poly(amidoamine) dendrimer-based drug carrier for delivering DOX to gliomas cells. RSC Advances, 7(25), 15475–15481. https://doi.org/10.1039/C7RA00713B

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