Local anesthetic plasma levels in children

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Abstract

Blood levels of lignocaine and bupivacaine were measured in children following caudal, subcutaneous and tracheal administration. The highest peak levels were in children under 3 years following tracheal spray but all blood levels were below accepted toxic adult levels for anaesthetised patients. No toxic manifestations were seen.

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Eyres, R. L., Kidd, J., Oppenheim, R., & Brown, T. C. K. (1978). Local anesthetic plasma levels in children. Anaesthesia and Intensive Care, 6(3), 243–247. https://doi.org/10.1177/0310057x7800600312

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