Evaluation of growth promotion and inhibition from mycobactins and nonmycobacterial siderophores (Desferrioxamine and FR160) in Mycobacterium aurum

Abstract

Heterologous mycobactins and the synthetic FR160 [N4-nonyl,N1,N8- bis(2,3-dihydroxybenzoyl) spermidine hydrobromide (C30H46N3 O6 Br)] promoted growth in Mycobacterium aurum in low concentrations. They were otherwise highly inhibitory, as opposed to homologous mycobactin, which was strictly growth promoting. Desferrioxamine B (Desferal) had no significant effect on growth.