Pitted keratolysis: Successful management with mupirocin 2% ointment monotherapy

Abstract

Background: Pitted keratolysis is a benign dermatosis that occurs on plantar skin. Purpose: We describe a man with pitted keratolysis that was successfully treated with mupirocin 2% ointment monotherapy. Methods and Materials: We reviewed PubMed for the following terms: mupirocin, ointment, pitted keratolysis, treatment. We also reviewed papers containing these terms and their references. Results: Complete resolution of pitted keratolysis occurred following monotherapy with twice daily application of mupirocin 2% ointment for a duration of three weeks. There was no recurrence at a follow-up visit eight weeks later. Conclusions: Several topical and oral treatments are available to successfully manage pitted keratolysis. Our patient confirms previous reports of pitted keratolysis resolving with mupirocin 2% ointment treatment. Monotherapy with mupirocin 2% ointment should be considered as a primary treatment alternative for pitted keratolysis.