A low percentage of patients with Type 2 diabetes and decreased adiponectin reach glycemic control

Abstract

Background: Few studies classify individuals with type 2 diabetes (T2D) according to their body weight and compare their serum adipokines after a period of treatment. Objective: To know what percentage of T2D patients achieved glycemic control. Material and method: This cross-sectional and analytical study included 84 individuals, distributed into four groups: control (CNN, n = 13), control with obesity (CON, n = 38), patients with T2D, overweight or obesity but normal glucose (DON, n = 12), and patients with T2D, overweight or obesity and high glucose (DOH, n = 21). The selection criteria for T2D patients were daily treatment with metformin and a diagnosis of T2D within five years. Results: The 34% of patients in the DON group exhibited adequate glycemic control; however, their serum adiponectin levels were low (p = 0.001) compared to the CON group. Conclusions: Although patients in the DON group achieved normal glucose, adiponectin levels were decreased in these T2D patients compared with controls.