Synthetic Studies on the Picraline-Type Indole Alkaloids-I: Improved Synthesis of C-Mavacurine-Type Compounds and a New Skeletal Rearrangement in a Corynanthe-Type Derivative

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Abstract

An efficient synthesis of the C/D ring-cleaved compounds (13S and 13R) from hirsutine (7) and their transformation into three different type of products, 8 (C-mavacurine type), 18 (isopleiocarpamine type), and 22 are described. © 1991, The Pharmaceutical Society of Japan. All rights reserved.

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Koike, T., Takayama, H., & Sakai, S. I. (1991). Synthetic Studies on the Picraline-Type Indole Alkaloids-I: Improved Synthesis of C-Mavacurine-Type Compounds and a New Skeletal Rearrangement in a Corynanthe-Type Derivative. Chemical and Pharmaceutical Bulletin, 39(7), 1677–1681. https://doi.org/10.1248/cpb.39.1677

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