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Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse

Clinical Infectious Diseases (2023) 76(3) E990-E994
DOI: 10.1093/cid/ciac445
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Abstract

Bacterial killing in patients with tuberculosis (TB) relapse was compared to that in patients achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria growth indicator tube (MGIT) time to positivity (TTP). TB-MBLA in 4 relapsed patients was significantly different compared to 132 cured patients after 2 weeks of treatment; MGIT TTP showed a significant difference from week 8.

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Ntinginya, N. E., Bakuli, A., Mapamba, D., Sabiiti, W., Kibiki, G., Minja, L. T., … Heinrich, N. (2023). Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse. Clinical Infectious Diseases, 76(3), E990–E994. https://doi.org/10.1093/cid/ciac445

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