Comparative Study between Two Doses of Intravenous Ondansetron on Maternal Haemodynamics during Elective Caesarean Delivery under Spinal Anaesthesia

Abstract

Background: Hypotension is one of the most common intra-operative complications associated with spinal anaesthe- sia. Its incidence in caesarean section has been estimated to be as high as 50-60%. Despite fluid preloading, lateral uterine displacement and the use of vasopressor agents. It occurs due to sympathetic block which leads to autonomic nervous system disturbances and a decrease in systemic vascular resistance. This can occur because the level of block must be at least at T4 to ensure adequate analgesia severe hypotension following spinal anaesthesia in caesarean section is a dangerous com- plication. If it is unnoticed or inadequately treated, it can lead to serious maternal or fetal compromise. Aim of Study: To evaluate the effect of two doses of prophylactic ondansetron on spinal anesthesia-induced hypo- tension and bradycardia among patients undergoing elective cesarean deliveries. Patients and Methods: This study was carried out in Ain Shams Hospital Obstetric Theatres from March 2020 to September 2020. Written informed consent was obtained from every parturient included in the study. Ethical approval for this study was provided by the Ethics Committee of Faculty of Medicine, Ain Shams University. FAMSU MS 155/2020 (FWA 000017585) 23/2/2020. Results: