Heidenhain variant of creutzfeldtjakob disease with concurrent findings of posterior reversible encephalopathy syndrome: A case report and literature review

Abstract

Although Creutzfeldt-Jakob disease is not yet proved to be related to the development of posterior reversible encephalopathy syndrome, prion invasion to the endothelium has been shown to change blood-brain barrier permeability. We present a case of Heidenhain variant of Creutzfeldt-Jakob disease that had associated imaging findings of posterior reversible encephalopathy syndrome, with a review of the literature, raising the question of whether Creutzfeldt-Jakob disease instead represents another cause for the development of posterior reversible encephalopathy syndrome.