A New Tetracycline Antibiotic With Antitumor Activity I. Taxonomy And Fermentation Of The Producing Strain, Isolation And Characterization Of Sf2575

Masahiro Hatsu; Toru Sasaki; Hiro Omi Watabe; Shinji Miyadoh; Mieko Nagasawa; Takashi Shomura; Masaji Sezaki; Shigeharu Inouye; Shinichi Kondo

Journal ArticleOPEN ACCESS

A New Tetracycline Antibiotic With Antitumor Activity I. Taxonomy And Fermentation Of The Producing Strain, Isolation And Characterization Of Sf2575

Journal of Antibiotics (1992) 45(3) 320-324

DOI: 10.7164/antibiotics.45.320

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Abstract

A new antitumor antibiotic SF2575 has been isolated from a culture filtrate of Streptomyces sp. SF2575. The molecular formula was determined to be C40H43NO15 by elemental analysis, mass and 13C NMR spectral analyses. The spectral data revealed SF2575 to be a new tetracycline antibiotic. It was active against Gram-positive bacteria and exhibited antitumor activity against p 388 leukemia in mice. © 1992, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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Hatsu, M., Sasaki, T., Watabe, H. O., Miyadoh, S., Nagasawa, M., Shomura, T., … Kondo, S. (1992). A New Tetracycline Antibiotic With Antitumor Activity I. Taxonomy And Fermentation Of The Producing Strain, Isolation And Characterization Of Sf2575. Journal of Antibiotics, 45(3), 320–324. https://doi.org/10.7164/antibiotics.45.320

A New Tetracycline Antibiotic With Antitumor Activity I. Taxonomy And Fermentation Of The Producing Strain, Isolation And Characterization Of Sf2575

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