Abstract
The novel antitumor antibiotic himastatin was isolated from cultured broth of Streptomyces hygroscopicus (ATCC 53653) and purified by vacuum liquid chromatography, column chromatography, and crystallization. Degradation and spectroscopic studies have shown that himastatin contains valine, leucine, threonine, α-hydroxyisovaleric acid, 5-hydroxypiperazic acid and a dimeric hexahydropyrroloindole system. © 1990, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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CITATION STYLE
Leet, J. E., Schroeder, D. R., Krishnan, B. S., & Matson, J. A. (1990). Himastatin, a new antitumor antibiotic from streptomyces hygroscopicus: II. Isolation and characterization. The Journal of Antibiotics, 43(8), 961–966. https://doi.org/10.7164/antibiotics.43.961
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