Variable linezolid exposure and response and the role of therapeutic drug monitoring: Case series

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Abstract

Two patients with normal renal function, yet each showed unexpected, supra- and subtherapeutic linezolid plasma concentrations resulting in toxicity and ineffective therapy, respectively. TDM helps to early identify and correct such excursions.

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Alghamdi, W. A., Al-Shaer, M. H., Klinker, K. P., & Peloquin, C. A. (2020). Variable linezolid exposure and response and the role of therapeutic drug monitoring: Case series. Clinical Case Reports, 8(7), 1126–1129. https://doi.org/10.1002/ccr3.2835

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