Abstract
Optically pure diketopiperazines were obtained in good yields when dipeptide esters were refluxed in 2-butanol containing 0.1 m acetic acid for 3 hours. When prolyl-amino acid ester was used as the starting material, 1 to 2 m acetic acid was the most effective concentration. © 1981, The Pharmaceutical Society of Japan. All rights reserved.
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APA
Suzuki, K., Sasaki, Y., Endo, N., & Mihara, Y. (1981). Acetic Acid-Catalyzed Diketopiperazine Synthesis. Chemical and Pharmaceutical Bulletin, 29(1), 233–237. https://doi.org/10.1248/cpb.29.233
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