Anti-Tumor Effect of Chinese Herbal Medicine “Sheng-Jin-Jie-Du-Yin” on a Human Maxillary Cancer Cell Line

Abstract

We evaluated the anti-tumor effect of the herbal medicine, Sheng-Jin-Jie-Du-Yin, on a human maxillary cancer cell line transplanted into nude mice. This herb consists of 16 crude drugs developed in China. We found it to be effective in inhibiting the cancer transplanted into animals. The two crude drugs, solanum lyratum herb and oldenlandia herb, in Sheng-Jin-Jie-Du-Yin accounted for the anti-tumor effect. The anti-tumor effect of solanum lyratum herb was noted when it was combined with radiotherapy, while oldenlandia herb was effective in the inhibition of tumor growth when given alone or in combination with radiotherapy. We measured the NK activities in nude mouse spleen cells and concluded that the anti-tumor effect of oldenlandia herb is related to an immune mechanism. © 1995, The Society of Practical Otolaryngology. All rights reserved.