Francisella tularensis : Biology, Pathogenicity, Epidemiology, and Biodefense

Abstract

Tularemia: history, epidemiology, pathogen physiology, and clinical manifestations / Anders Sjöstedt -- Molecular ecology, epidemiology and evolution of Francisella / Paul Keim, Anders Johannson, and David M. Wagner -- Genetics and genetic manipulations in Francisella tularensis / Dara W. Frank and Thomas C. Zahrt -- Francisella tularensis genomics and proteomics / Richard W. Titball and Joseph F. Petrosino -- The Francisella pathogenicity island / Francis E. Nano and Crystal Schmerk -- Molecular and genetic basis of pathogenesis in F. tularensis / Jeffrey R. Barker and Karl E. Klose -- Uptake and intracellular fate of Francisella tularensis in human macrophages / Daniel L. Clemens and Marcus A. Horwitz -- Type II secretion and type IV pili of Francisella / Åke Forsberg and Tina Guina -- The structure and function of Francisella lipopolysaccharide / John S. Gunn and Robert K. Ernst -- Francisella tularensis: activation of the inflammasome / David S. Weiss, Thomas Henry, and Denise M. Monack -- Animal models of Francisella tularensis infection / C. Rick Lyons and Terry H. Wu -- Mucosal immunopathogenesis of Francisella tularensis / Dennis Metzger, Chandra Shekhar Bakshi, and Girish Kirimanjeswara -- Innate and adaptive immunity to Francisell / Karen L. Elkins, Siobhán C. Cowley, and Catharine M. Bosio -- Vaccines against Francisella tularensis / J. Wayne Conlan and Petra C.F. Oyston -- Pneumonic tularemia on Martha's Vineyard: clinical, epidemiologica and ecological characteristics / Bela T. Matyas, Henry S. Nieder, and Sam R. Telford III -- New approaches to diagnosis and therapy of tularemia / Arne Tärnvik and May C. Chu -- Biosafety and selectable markers / Rick W. Titball [and others].