Reverse micellar systems as a versatile tool on halophilic biocatalysts

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Abstract

Halophilic biocatalysts offer wide insight through unique properties making them suitable to interact with reverse micellar systems on nonconventional media, where these microemulsions work as nanoreactors able to protect enzymes from harsh operating conditions. However, this robust technology till now is limited due to few studies on industrial-scale approaches and, by the surfactant and organic solvent nature. Therefore reverse micelles are prowess for biotechnological applications in order to enhance enzymatic activity and stability. Research survey reveals that, with low water content in the reverse micelle core, it is possible to lead to new enzymatic reactions employing less water-soluble substrates that favor an increase in substrate concentration, and consequently, reaction rates and yields. The present review projects a glimpse on reverse micellar systems that highlights the attractive biocatalysis potential, in order to subject halophilic enzymes into harsh industrial conditions. Also, to address some significant halophilic biocatalyst developments in biotechnology.

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Márquez-Villa, J. M., Mateos-Díaz, J. C., Rodríguez-González, J. A., & Camacho-Ruíz, R. M. (2022). Reverse micellar systems as a versatile tool on halophilic biocatalysts. In Extremozymes and their Industrial Applications (pp. 353–373). Elsevier. https://doi.org/10.1016/B978-0-323-90274-8.00006-X

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