Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin

undefined; Elizabeth J. Ziegler; Charles J. Fisher; Charles L. Sprung; Richard C. Straube; Jerald C. Sadoff; Garrett E. Foulke; Cornelis H. Wortel; Mitchell P. Fink; R. Phillip Dellinger; Nelson N.H. Teng; I. Elaine Allen; Harvey J. Berger; Genell L. Knatterud; Albert F. LoBuglio; Craig R. Smith

Journal ArticleOPEN ACCESS

Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin

Ziegler E
Fisher C
et al.

New England Journal of Medicine (1991) 324(7) 429-436

DOI: 10.1056/nejm199102143240701

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Abstract

A-1A is a human monoclonal IgM antibody that binds specifically to the lipid A domain of endotoxin and prevents death in laboratory animals with gram-negative bacteremia and endotoxemia

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APA

Ziegler, E. J., Fisher, C. J., Sprung, C. L., Straube, R. C., Sadoff, J. C., … Smith, C. R. (1991). Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin. New England Journal of Medicine, 324(7), 429–436. https://doi.org/10.1056/nejm199102143240701

Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin

Abstract

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