Antibacterial activity of di-2-ethylaniline phosphate screened by paper disc diffusion method

Abstract

Antibacterial activity di-2-ethylaniline phosphate was studied against four Gram negative bacteria at 100-10000 μg/ml concentration using the paper disc diffusion method. Results indicated that the test compound, di-2-ethylaniline phosphate has demonstrated significant antibacterial activity against all selected Gram negative bacteria. Di-2-ethylaniline phosphate was found to be effective against bacteria A at lowest concentration 100 μg/ml where the zone of inhibition was 9 mm diameter in size and largest zone 24 mm diameter formed at highest concentration 10000 μg/ml against bacteria D while bacteria B and C exhibited more resistance as compared to bacteria A and D. In conclusion di-2-ethylaniline phosphate exhibited an efficient antibacterial activity.