In recent years, there have been an increasing number of infections due to multidrug-resistant organisms in the neonatal intensive care unit. Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a challenge in clinical anti-infection treatment. Herein, we report the case of CRKP sepsis in an extremely low-birth weight infant (ELBWI) who did not respond to meropenem and vancomycin, but was treated successfully after a 10-day antibiotic course with trimethoprim–sulfamethoxazole (TMP-SMZ). Recent research on CRKP-associated sepsis and the application of TMP-SMZ therapy in children and neonates were reviewed to offer a reference for clinical practice.
CITATION STYLE
Weng, B., Zhang, X., Hong, W., Yan, C., Gong, X., & Cai, C. (2021). A case of sepsis due to carbapenem-resistant klebsiella pneumoniae in an extremely low-birth weight infant treated with trimethoprim– sulfamethoxazole. Infection and Drug Resistance, 14, 2321–2325. https://doi.org/10.2147/IDR.S312183
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