Barshop Symposium on Aging 2018 Abstracts

Abstract

The proceedings contain 28 papers. The topics discussed include: the effect of metformin treatment and voluntary exercise on Alzheimer's disease related neuropathology in a female transgenic mouse model; Ldlr-related protein 1 increases cytokine sensitivity implications for recovery after brain damage; unacylated ghrelin prevents skeletal muscle atrophy and contractile dysfunction in sarcopenia; aster-b regulates cholesteryl ester trafficking to mitochondria; investigating the loss of terminal neuronal differentiation as a novel mechanism driving neuronal death in Alzheimer's disease and related tauopathies; linking gut microbiome composition and tlr4-mediated endotoxemia to insulin resistance and type 2 diabetes; and oxidative stress is associated with muscle damage without a myogenic response.