Quinalizarin as a potential antifungal drug for the treatment of Candida albicans fungal infection in cancer patients

  • Janeczko M
  • Kochanowicz E
  • Górka K
  • et al.
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Abstract

This article is a study to determine the antifungal activity of quinalizarin (1,2,5,8-tetrahydroxyanthraquinone). Quinalizarin has potential antitumor properties and is effective in different types of tumor cells. The aim of the present study was to prove that quinalizarin can be used simultaneously in the treatment of cancer and in the treatment of intercurrent fungal infections. Quinalizarin was identified as a novel antifungal compound with low toxicity. These results may contribute to the development of a new drug with dual activity in the treatment of cancer-associated candidiasis.

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Janeczko, M., Kochanowicz, E., Górka, K., & Skrzypek, T. (2024). Quinalizarin as a potential antifungal drug for the treatment of Candida albicans fungal infection in cancer patients. Microbiology Spectrum, 12(3). https://doi.org/10.1128/spectrum.03652-23

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