Perspective: Stabilizing the microbiome skin-gut-brain axis with natural plant botanical ingredients in cosmetics

Abstract

The microbiome of the gut and skin have recently been shown to have a strong connection through the host immune system. Various skin and gut inflammatory conditions are interrelated and connected through intricate immune pathways that affect the host barrier functions both in the skin and the gut. Microbiome 'dysbiosis' of the skin and gut leads to various alterations in host immune pathways that can alter the barrier and lead to disease. In this perspective article, we discuss the role of plant botanicals in cosmetics and their effect on the skin-gut-brain axis.