Mineralocorticoid-receptor signalling in vascular smooth muscle

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Abstract

Human data suggest that eplerenone and spironolactone lowers blood pressure by mechanisms independent of the distal tubule. Now, a novel inducible conditional knockout model of the mineralocorticoid receptor (MR) in vascular smooth muscle cells (VSMCs) brings out understanding further. © 2013 The Authors.

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Wu, J., & Luft, F. C. (2013, June). Mineralocorticoid-receptor signalling in vascular smooth muscle. Nephrology Dialysis Transplantation. https://doi.org/10.1093/ndt/gfs562

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