Further Isolations of Reovirus Type 3 from Cases of Burkitt's Lymphoma

Abstract

Twelve strains of virus have been isolated from nine cases of Burkitt's lymphoma. Ten of these, from seven cases, are reovirus type 3. One of the others appears to be herpes simplex, while the twelfth has not yet been identified. The appearance of these reovirus strains in the electron microscope and their effects on mice were characteristic, and it is concluded that reovirus is associated with at least a proportion of the cases of Burkitt's lymphoma. The implications of these findings are discussed in the light of new epidemiological evidence. © 1966, British Medical Journal Publishing Group. All rights reserved.