Atherosclerosis

Abstract

Atherosclerosis and its complications contribute to a large percentage of morbidity and mortality in older people. Cardiovascular disease is the leading worldwide cause of morbidity and death.1 However, our understanding of the pathogenetic mechanisms underlying atherosclerosis and its complications remain incomplete, since more than half of patients with atherosclerosis do not show classical risk factors, such as hypercholesterolemia, hypertension, smoking history, diabetes, obesity, or sedentary life style.1,2.