Increased force variability in chronic stroke: Contributions of force modulation below 1 Hz

Abstract

Increased force variability constitutes a hallmark of arm disabilities following stroke. Force variability is related to the modulation of force below 1 Hz in healthy young and older adults. However, whether the increased force variability observed post stroke is related to the modulation of force below 1 Hz remains unknown. Thus, the purpose of this study was to compare force modulation below 1 Hz in chronic stroke and age-matched healthy individuals. Both stroke and control individuals (N = 26) performed an isometric grip task to submaximal force levels. Coefficient of variation quantified force variability, and power spectrum density of force quantified force modulation below 1 Hz with a high resolution (0.07 Hz). Analyses indicated that force variability was greater for the stroke group compared with to healthy controls and for the paretic hand compared with the non-paretic hand. Force modulation below 1 Hz differentiated the stroke individuals and healthy controls, as well as the paretic and non-paretic hands. Specifically, stroke individuals (paretic hand) exhibited greater power ∼0.2 Hz (0.07-0.35 Hz) and lesser power ∼0.6 Hz (0.49-0.77 Hz) compared to healthy controls (non-dominant hand). Similarly, the paretic hand exhibited greater power ,0.2 Hz, and lesser power ∼0.6 Hz than the nonparetic hand. Moreover, variability of force was strongly predicted from the modulation of specific frequencies below 1 Hz (R2 = 0.80). Together, these findings indicate that the modulation of force below 1 Hz provides significant insight into changes in motor control after stroke. © 2013 Lodha et al.