Advances in Fibre Microendoscopy for Neuronal Imaging

Abstract

Traditionally, models for neural dynamics in the brain have been formed through research conducted on slices, with electrodes, or by lesions to functional areas. Recent developments in functional dyes and optogenetics has made brain research more accessible through the use of light. However, this improved accessibility does not necessarily apply to deep regions of the brain which are surrounded by scattering tissue. In this article we give an overview of some of the latest methods in development for neural measurement and imaging.We specifically address methods designed to overcome the problem of imaging invivo for regions far beyond the mean free path of photons in brain tissue. These methodswould permit previously restricted neural research.