Influence of MgO on Sol-Gel Derived SiO2-CaO-Na2O-P2O5 Bioglass System

Abstract

Sol-gel derived SiO2-CaO-Na2O-P2O5 (45S5) bioactive glass (BG) is well known for its enhanced bioactivity properties towards bone regeneration. The synthesis of 45S5 and the addition of MgO (1, 2, 3 and 5 mole percentages) in the 45S5 system was prepared using sol-gel method. The prepared bioactive glass powder was immersed in simulated body fluid (SBF) at room temperature for 7 days. The effect of MgO on the BG structure and bioactivity were characterized through X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The results showed that increasing MgO concentration within the 45S5 influenced the glass structural phases formation. In addition, FTIR proved the presence of Si-O bending and Si-O stretching as the main transmission bonds. The addition of MgO affected the apatite layer formation on the glass surface following SBF bioactivity test.