Successful topical rapamycin treatment for facial angiofibromata in two children

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Abstract

Topical sirolimus, or rapamycin, is known to inhibit tumorigenesis in tuberous sclerosis. We report two cases of successful treatment of children with facial angiofibromata and summarize the encouraging evidence of the effectiveness of this therapy in the literature.

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Pynn, E. V., Collins, J., Hunasehally, P. R. Y., & Hughes, J. (2015). Successful topical rapamycin treatment for facial angiofibromata in two children. Pediatric Dermatology, 32(3), e120–e123. https://doi.org/10.1111/pde.12551

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